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Autologous Retinal Transplant in Refractory Macular Holes.


ABSTRACT: Purpose: To report the structural and functional outcomes of autologous neurosensory retinal transplant for closure of refractory macular holes (MHs) and to highlight the long-term follow-up findings. Methods: Nine eyes of 9 patients with full-thickness MH refractory to previous vitrectomy with internal limiting membrane (ILM) peeling and tamponade underwent pars plana vitrectomy, autologous retinal transplant with short-term perfluoro-n-octane heavy liquid, followed by gas tamponade. Patients were followed for 12.7 ± 10 months (range, 3-32 months). Results: Optical coherence tomography showed complete anatomic closure of the MH in 8 of 9 eyes (89%). Restoration of the outer retina and integration of the neurosensory retinal flap were noted in 5 eyes. The mean correcte

SUBMITTER: Al-Assil T 

PROVIDER: S-EPMC12357837 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature