Fourteen years later: Reviewing the diagnostic criteria for behavioral-variant frontotemporal dementia.

ABSTRACT:

Introduction

Diagnosis of behavioral-variant frontotemporal dementia (bvFTD) requires the presence of at least three of six core features. The contribution of each criterion toward diagnosis, however, remains unclear. We aimed to determine the frequency and combinations of diagnostic criteria at presentation and their contribution to survival.

Methods

Consecutive patients with a stable diagnosis of bvFTD between 2010 and 2023 were included. Demographic and cognitive data were also collected.

Results

A total of 110 patients were identified. Frequency of diagnostic criteria ranged from 89% (apathy; empathy loss) to 14.5% (dysexecutive profile), and 78 patients met at least four criteria. Mean survival time from symptom onset was 10.4 years and was not affected by the nu

SUBMITTER: Piguet O 

PROVIDER: S-EPMC12358242 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature