Increased mortality in patients with non-functioning pituitary tumors: a study in a tertiary center.

ABSTRACT:

Background information

Most of the studies on mortality, survival analysis and predictor variables in patients with non-functioning pituitary adenomas (NFPA) are heterogeneous and limited; and in some cases, they offer contradictory results.

Patients and methods

Our objective was to analyze the survival of 749 patients (46.3% were women) with NFPA, with a mean follow-up of 60.2 months (32.9-120.6) at a tertiary center, from March 2007 to August 2023. Descriptive and inferential statistics were used. Mortality risk was determined in comparison with the Mexican population by calculating the standardized mortality ratio (SMR) with 99% confidence intervals. Survival analysis and Cox proportional hazards (HR) analysis were performed to identify possible predictors.

Results

SUBMITTER: Vargas-Ortega G 

PROVIDER: S-EPMC12358282 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature