Umbrella review of photodynamic therapy for cancer: efficacy, safety, and clinical applications.

ABSTRACT:

Background

Photodynamic therapy (PDT) can target cancers, while causing little damage to surrounding healthy tissues.

Objective

To systematically evaluate the efficacy, safety, and clinical applications of PDT across cancer types.

Methods

PubMed, EMBASE, Cochrane Library, and Web of Science were searched to April 7, 2024 for systematic reviews and meta-analyses of PDT in patients with cancer. Quality assessment was performed using Assessment of Multiple Systematic Reviews 2, overlapping meta-analyses were handled using Corrected Covered Area, and data re-synthesized using a random-effects model.

Results

Eighteen publications met the inclusion criteria. There is weak evidence that PDT combined with biliary stenting improves overall survival (OS) relative to sten

SUBMITTER: Chen H 

PROVIDER: S-EPMC12358287 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature