Inter-reader agreement and additive benefit of SPECT or SPECT/CT modality with [^99mTc]Tc-pertechnetate scintigraphy imaging for the assessment of thyroid nodules in a tertiary care center.

ABSTRACT:

Aim/introduction

In central Europe, up to 76% of population exhibit thyroid nodules (TN). The combination of ultrasound findings and thyroid scan imaging are supposed to ensure a cost-effective and reliable prediction of malignancy risk. However, real-world impact of ultrasound findings, i.e. TI-RADS, has raised concerns due to its highly limited reliability and reproducibility. The recent advancements and increasing access of SPECT/CT scanners might contribute to thyroid management. This study aimed to elucidate additive value of SPECT(-CT) imaging in initial evaluation of complex TN cases, particularly on multinodular goiter and difficult-to-characterize solitary nodules.

Materials and methods

A total of 61 patients (19 males and 42 females with a mean age of 56 (± 17)) wi

SUBMITTER: Novruzov E 

PROVIDER: S-EPMC12358339 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature