Impact of chest computed tomography-determined low skeletal muscle mass on the survival of patients with acute heart failure.

ABSTRACT:

Background

Computed tomography (CT)-determined low skeletal muscle mass (SMM) has been reported to be associated with poor clinical outcomes in various diseases; however, limited information is available regarding patients with heart failure (HF). Our research aimed to investigate the prognostic significance of low SMM assessed by chest CT scans in hospitalized patients with acute heart failure (AHF).

Methods

Skeletal muscle index (SMI) was assessed using chest CT scans at the twelfth thoracic vertebra (T12) level, and sex-specific optimal cutoff values for T12 SMI were determined using the X-tile program based on all-cause mortality. The outcomes of this study were all-cause death and cardiovascular death. Cox proportional hazards models were employed to identify the risk f

SUBMITTER: Huang Y 

PROVIDER: S-EPMC12358454 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature