Sex differences in clinical risk factors for Alzheimer's dementia patients with early-onset and late-onset.

ABSTRACT:

Background

The objective of this study is to identify the risk factors that contribute to sex differences in patients with Alzheimer dementia (AD), specifically focusing on Early-Onset Alzheimer's Dementia (EAOD) and Late-Onset Alzheimer Dementia (LOAD). Additionally, the study aims to determine whether these risk factors differ between male and female EAOD and LOAD patients.

Methods

Our retrospective cohort study included a total of 6,212 patients diagnosed with either EOAD or LOAD from February 2016 to August 2020. Among this population, 687 patients (11.06%) were diagnosed with EOAD, while 5,525 patients (88.94%) had LOAD. We conducted a univariate analysis to identify differences in risk factors between male and female AD patients. A multivariate analysis was also perfor

SUBMITTER: Faulstich NG 

PROVIDER: S-EPMC12358484 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature