Weight change across adulthood in relation to the risk of COPD.

ABSTRACT:

Background

Despite some studies identifying a potential association between obesity and chronic obstructive pulmonary disease (COPD) risk, previous research had overlooked the dynamic nature of body weight over time, leading to inconsistent findings. The purpose of this study is to elucidate the relationship between adult weight change and COPD risk by adjusting for potential confounding factors.

Methods

We conducted a retrospective analysis using data from ten NHANES cycles (1999-2018), including adults aged 40-74 years. Weight change patterns were assessed using BMI at three time points and classified into five categories per period. Absolute weight change was also grouped into five levels. Multivariate logistic regression models, incorporating sampling weights, were used

SUBMITTER: Gong E 

PROVIDER: S-EPMC12358758 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature