Human eyelid behavior is driven by segmental neural control of the orbicularis oculi.

ABSTRACT: The eyelid performs critical functions to protect the eye and preserve functional vision. These functions are driven by contraction of the orbicularis oculi (OO), which is a unique skeletal muscle with a circular geometry and diffuse innervation. It is thought that this distributed innervation may allow for differential segmental activation and contraction, but it is not currently understood how sequenced activation patterns relate to differential muscle contraction, nor how segmental contraction creates the kinematics that drive the eyelid's critical functions. In fact, motion of the eyelid has predominantly been modeled in only a single dimension (open-close). Here, we show that eyelid motion has important two-dimensional features that vary between eyelid behaviors. Using distributed int

SUBMITTER: Kim J 

PROVIDER: S-EPMC12358864 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature