Functional coupling of the lateral prefrontal cortex and the default mode network predicts performance in mental rotation.

ABSTRACT: Mental transformations, such as mental rotation, rely on motor representations and engage neural processes similarly to physical actions. Neuroimaging studies reveal that mental rotation activates the occipito-parietal cortex and motor-related areas, with differences based on whether stimuli are bodily or non-bodily. These findings emphasize the role of frontoparietal networks in mental rotation, similar to those used in motor planning. This study investigated whether resting-state functional connectivity of the left lateral prefrontal cortex (lPFC), a region linked to motor planning, and other functional brain networks predicts mental rotation performance. Fifty-nine healthy individuals underwent functional magnetic resonance imaging (fMRI) to capture resting-state blood oxygenation level

SUBMITTER: Ptak R 

PROVIDER: S-EPMC12358948 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature