Genomic evolution, antimicrobial resistance, and dissemination of global <i>Serratia</i> spp. unveil increasing species diversity and carbapenemae‑resistance: A retrospective and genomic epidemiology study.

ABSTRACT: Serratia spp., an opportunistic pathogen, has increasingly acquired resistance, particularly the emergence of carbapenemase-resistance. However, previous studies have focused on fragmented surveillance and have not conducted overall correlation. Here, 3769 non-duplicate Serratia genomes from sixty-five different countries across seven continents were classified into thirty-seven bacterial species, with 14 novel genospecies. The most common species was S. sarumanii, followed by S. nevei and S. marcescens. 809 novel STs were determined, which was more than double the number of known STs, with ST 367 and ST324 being the most predominant. 26.6 % (1001/3769) of Serratia isolates were carbapenemase-resistant. These resistant isolates were first identifie

SUBMITTER: Zhu W 

PROVIDER: S-EPMC12358953 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature