Tier-based standards for FAIR sequence data and metadata sharing in microbiome research.

ABSTRACT: Microbiome research is a growing, data-driven field within the life sciences. While policies exist for sharing microbiome sequence data and using standardized metadata schemes, compliance among researchers varies. To promote open research data best practices in microbiome research and adjacent communities, we (i) propose two tiered badge systems to evaluate data/metadata sharing compliance, and (ii) developed an automated evaluation tool to determine adherence to data reporting standards in publications with amplicon and metagenome sequence data. In a systematic evaluation of publications (n = 2929) spanning human gut microbiome research, and case studies of soil and gut microbiota (n = 370), we found nearly half do not meet minimum standards for sequence data availability. Moreover, poor

SUBMITTER: Kim L 

PROVIDER: S-EPMC12359039 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature