The Cumulative Atherogenic Index of Plasma Exposure in Carotid Plaque: A Cohort Study in China.

ABSTRACT:

Background

Atherogenic index of plasma (AIP) is recognized as a marker for atherosclerosis, but the impact of long-term AIP exposure on carotid plaque remains unknown.

Objectives

The objective of the study is to assess the associations of cumulative AIP (cumAIP), incorporating the time course of cumAIP accumulation with the risk of carotid plaque.

Methods

A total of 9,202 participants from the Beijing Health Management Cohort were followed up until December 31, 2021. AIP was calculated as the logarithm of the ratio of triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C). CumAIP was derived by averaging AIP values between consecutive visits and multiplying by time intervals. HRs and 95% CIs were calculated using an adjusted Cox proportional hazards model t

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC12359051 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature