Multi-Institutional Audit of FLASH and Conventional Dosimetry With a 3D Printed Anatomically Realistic Mouse Phantom.

ABSTRACT:

Purpose

We conducted a multi-institutional dosimetric audit between FLASH and conventional dose rate (CONV) electron irradiations by using an anatomically realistic 3-dimensional (3D) printed mouse phantom.

Methods and materials

A computed tomography (CT) scan of a live mouse was used to create a 3D model of bony anatomy, lungs, and soft tissue. A dual-nozzle 3D printer was used to print the mouse phantom using acrylonitrile butadiene styrene (∼1.02 g/cm³) and polylactic acid (∼1.24 g/cm³) simultaneously to simulate soft tissue and bone densities, respectively. The lungs were printed separately using lightweight polylactic acid (∼0.64 g/cm³). Hounsfield units (HU), densities, and print-to-print stability of the phantoms were assessed. Three i

SUBMITTER: Ashraf MR 

PROVIDER: S-EPMC12359262 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature