The effect of topical antibiotic or antibiotic-corticosteroid treatment on the ocular surface microbiota of healthy horses.

ABSTRACT:

Introduction

Information regarding the impact of topical antibiotics with or without corticosteroids on the microbiota of the horses' eyes is limited. This study aimed to describe the bacterial ocular surface microbiota in healthy horses and evaluate the effect of topical antibiotics or antibiotic-corticosteroid medication on the ocular surface microbiota.

Methods

This was a prospective, randomized, longitudinal, blinded study in which one eye of 12 horses was treated 3 times daily for 7 days with neomycin, polymyxin B and bacitracin ophthalmic ointment (n = 6) or neomycin, polymyxin B and dexamethasone ophthalmic ointment (n = 6). The contralateral eyes operated as untreated controls. The inferior conjunctival fornix of both eyes was sampled at baseline before

SUBMITTER: Martin de Bustamante MG 

PROVIDER: S-EPMC12359475 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature