Gluten-free diet adherence patterns and health outcomes in celiac disease: a retrospective observational study.

ABSTRACT:

Background

Celiac disease (CeD) is an autoimmune disorder, causing significant gastrointestinal (GI) and non-GI symptoms. The only effective treatment is a gluten-free diet (GFD), but adherence can be challenging. This study investigates GFD adherence among CeD patients and the change in their clinical and pathological conditions over time.

Methods

A telephone-based retrospective observational analysis conducted between November 2022 and June 2023 enrolled 300 participants with confirmed CeD, selected via systematic sampling from an initial cohort of 1,268 individuals. A comprehensive questionnaire assessed demographics, clinical symptoms, and GFD adherence. Participants were categorized into short/meidum-term (≤ 6 months), long-term (6-24 months), and very long-term (≥ 24 m

SUBMITTER: Rahimi S 

PROVIDER: S-EPMC12359905 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature