Accuracy of two Sepsityper MALDI-TOF MS methods for bacterial identification in bloodstream infections in dogs, foals, and calves using Bayesian latent class model.

ABSTRACT: Accurate diagnosis of bloodstream infections is crucial for survival and antimicrobial de-escalation in veterinary medicine. Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry enables faster identification of bacteria in BSIs. This study aimed to compare diagnostic accuracy of two Sepsityper^® methods (Rapid Sepsityper^® and Sepsityper^® Extraction) with conventional culture method for bacterial identification in clinical samples. Mean time-to-positivity and frequency of bacteria in BSIs were also determined. This diagnostic test study used bloodstream infection samples from 385 critically ill animals (121 dogs, 119 foals, and 145 calves) admitted to the Faculty of Veterinary Medicine, Ghent (October 2021-February 2024). Accuracy was

SUBMITTER: Castelain D 

PROVIDER: S-EPMC12360051 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature