Antibiotic Use in Pediatric Dengue Cases in Taiwan: A National Administrative Database Analysis.

ABSTRACT: Nonspecific dengue clinical manifestations lead to avoidable antibiotic use. We describe antibiotic use in confirmed pediatric dengue cases and associated healthcare utilization and medical costs, including from antibiotic-associated adverse drug events (ADEs). From Taiwanese national administrative databases, children with confirmed dengue between 2009 and 2015 who were younger than 18 years old, without bacterial infection, and who were prescribed antibiotics a week before or after laboratory diagnosis were propensity score matched and compared with nonrecipients, using regression models for ADEs and medical care expenditures. A total of 1,959 out of 6,938 children (28.2%) with confirmed dengue without bacterial infection received antibiotics. Recipients were more likely to incur emergen

SUBMITTER: Shen YJ 

PROVIDER: S-EPMC12360090 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature