Association between serum lipase levels and chronic kidney disease stages.

ABSTRACT:

Objective

To explore the relationship between serum lipase levels and chronic kidney disease (CKD) progression, evaluating its usefulness in assessing efficacy, severity, and predicting outcomes in CKD.

Methods

This retrospective study analyzed 251 CKD patients treated at our hospital from January 2018 to December 2023, categorizing them into four groups based on 2022 Chinese and 2024 KDIGO guidelines. Clinical and biochemical data, including serum lipase, Scr, and BUN were collected. Additionally, a supplementary cohort of 50 CKD patients treated between January 2024 and March 2025 was included to support the findings.

Results

Serum lipase levels increased with advancing CKD stages [G1-2: 40.50 (30.75,52.00), G3:47.00 (37.25,61.00), G4:100.00 (77.00,126.00), G5:155.5

SUBMITTER: Zhang G 

PROVIDER: S-EPMC12360523 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature