Phantom for fluorescence uniformity and distortion assessment of near-infrared fluorescence guided surgery systems.

ABSTRACT:

Significance

The expanding use of fluorescence in surgery necessitates standardized characterization methods to facilitate reproducibility and regulatory review of imaging devices. Current guidelines suggest the use of optical phantoms as tools to quantify optical system performance, yet measurements of uniformity and spatial accuracy or distortion remain challenging and are performed in an ad hoc manner or not collected at all.

Aim

We introduce a photostable solid phantom, the reference uniformity and distortion (RUD) phantom, and accompanying analysis code for characterizing fluorescence uniformity and geometric distortion (GD). In addition, the concept of fluorescence flat-field correction is explored using this phantom.

Approach

The RUD phantom was imaged on a cus

SUBMITTER: Mannoh EA 

PROVIDER: S-EPMC12360714 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature