Association between oxidative balance score with cardiovascular - kidney - metabolic syndrome and all-cause mortality among US population.

ABSTRACT: Cardiovascular-Kidney-Metabolic (CKM) syndrome is a multi-stage condition with significant public health implications. The oxidative balance score (OBS), which integrates dietary and lifestyle pro-oxidants and antioxidants, offers a novel approach for evaluating oxidative stress in relation to CKM stages and outcomes. This study aimed to investigate the association between OBS and advanced CKM stages, as well as its relationship with all-cause mortality in a US population. Data were derived from the National Health and Nutrition Examination Survey. CKM stages were classified based on published criteria, and OBS was calculated using 20 components reflecting oxidative stress balance. Logistic regression and Cox proportional hazards models were applied to evaluate the associations between OBS

SUBMITTER: Shi L 

PROVIDER: S-EPMC12360915 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature