Case Report: Eccentric purulent pericarditis treated by PTCA guidewire-based pericardiocentesis and intrapericardial alteplase.

ABSTRACT: Purulent pericarditis is an infectious condition characterized by purulent pericardial effusion. In this case report, we present a 60-year-old male admitted with intermittent chest pain and fever, ultimately diagnosed with primary purulent pericarditis. Imaging revealed an eccentric loculated pericardial effusion, posing significant challenges for conventional pericardiocentesis. In this context, we innovatively employed a percutaneous transluminal coronary angioplasty (PTCA) guidewire-based pericardiocentesis technique, achieving successful catheter placement followed by intrapericardial administration of 5 mg alteplase. During follow-up, the patient achieved complete clinical recovery. This report introduces a PTCA guidewire-based pericardiocentesis approach, which safely addresses compl

SUBMITTER: Li C 

PROVIDER: S-EPMC12361241 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature