Life-years lost associated with mental disorders in people with HIV: a cohort study in South Africa, Canada and the United States.

ABSTRACT:

Introduction

People with HIV (PWH) have a high burden of mental health disorders, which contribute to increased mortality due to elevated rates of physical illness, suicide or fatal accidents. Additionally, mental health disorders can adversely affect antiretroviral therapy (ART) adherence, leading to increased HIV-related mortality. This study aims to quantify the difference in mortality between PWH who have a mental health disorder and PWH without mental health disorders in South Africa (SA) and North America (NA).

Methods

This cohort study includes PWH aged 18 years or older who initiated ART between 2000 and 2021 at a national private-sector HIV programme in SA and 13 programmes in the United States and Canada. Mental health disorders were diagnosed according to ICD-10 c

SUBMITTER: Ruffieux Y 

PROVIDER: S-EPMC12361348 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature