Gender-specific associations of metabolic and circadian syndromes with melanoma risk: insights from NHANES 2007-2018.

ABSTRACT: Melanoma incidence is increasing worldwide, prompting exploration into novel risk factors beyond traditional exposures like ultraviolet radiation. Recent studies suggest that metabolic and circadian disruptions may also contribute to melanoma development, yet their influence is poorly understood. This study examines the relationships between metabolic syndrome (MetS), circadian syndrome (CircS) and melanoma risk, emphasizing differences between different genders. Using National Health and Nutrition Examination Survey (NHANES) data (2007-2018), this cross-sectional study applied logistic regression to assess MetS and CircS associations with melanoma risk, adjusting for demographic and lifestyle factors. Receiver operating characteristic curves evaluated predictive ability, and restricted cu

SUBMITTER: Chen Y 

PROVIDER: S-EPMC12361359 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature