A study of the correlation between urinary perchlorate, nitrate, thiocyanate, and serum liver function indices.

ABSTRACT: This study explored relationship between concentrations of perchlorate, nitrate, and thiocyanate and serum liver function markers using data from 3366 adults in the 2013-2018 National Health and Nutrition Examination Survey (NHANES) of the United States. Generalized linear model (GLM), restricted cubic spline (RCS) regression model, and quartile g-computation (Qgcomp) regression model were used to assess the relationship. The median concentrations of perchlorate, nitrate, and thiocyanate in urine were 2.33, 42,900, and 1060 ng/mL. The median concentrations for serum liver function indicators were albumin (ALB, 4.2 g/dL), alkaline phosphatase (ALP, 67 IU/L), aspartate aminotransferase (AST, 22 U/L), alanine aminotransferase (ALT, 20 U/L), globulin (GLB,2.9 g/dL), gamma-glutamyl transferase

SUBMITTER: Zhang W 

PROVIDER: S-EPMC12361364 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature