Integrating visceral protein ratios and mid-arm circumference predicts survival and malnutrition in gastric cancer.

ABSTRACT: Gastric cancer, a leading cause of cancer-related mortality globally, lacks robust biomarkers for comprehensive prognosis. Accordingly, we examined the prognostic utility of combining the albumin-prealbumin-globulin ratio (APGR) with mid-arm circumference (MAC) for assessing survival, malnutrition, and metastasis in gastric cancer. A multicenter cohort comprising 1,803 patients with gastric cancer was categorized into three groups based on APGR and MAC values: normal, moderate-risk, and high-risk grades. Associations with overall survival (OS), malnutrition, and metastasis were evaluated using Cox proportional hazard regression and logistic regression analyses. Normal grade patients exhibited the highest OS (68.6%), followed by those with medium-risk (53.9%) and high-risk (39.9%) grades (P

SUBMITTER: Xian S 

PROVIDER: S-EPMC12361450 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature