Discovery of intestinal microorganisms that affect the improvement of muscle strength.

ABSTRACT: This study provides the first evidence related to the identification of microbial strains closely associated with muscle strength enhancement, independent of the host's genetic background. Fecal transplants from humans into mice revealed a significant impact of gut bacteria on muscle strength, with some mice experiencing increases, while others showed no change or decreases. Interestingly, analysis of the fecal and gastrointestinal tract bacteria from each mouse classified by the degree of muscle strength revealed significant differences based on muscle strength. Furthermore, a more diverse microbial community was observed in the gastrointestinal tract compared to the feces. Further investigation identified two bacterial species, Lactobacillus johnsonii (L. johnsonii) and Limosilactobacill

SUBMITTER: Ahn JS 

PROVIDER: S-EPMC12361556 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature