Dual-functionality of Nocardiopsis alba B57 in biocontrol and plant growth: a metabolomic approach to agricultural sustainability.

ABSTRACT: The increasing incidence of fungal phytopathogens poses a significant challenge to agricultural sustainability, necessitating the development of environmental alternatives to synthetic fungicides and mitigating their ecological impact. This study explores the efficiency of Nocardiopsis alba B57 to produce secondary metabolites with antifungal and plant growth-promoting properties. Untargeted metabolomics using ultra-high-performance liquid chromatography (UPLC-MS/MS) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses identified key metabolites (e.g., carbapenem, menaquinone, and fumiquinazoline) in the co-culture environment with fungal pathogens. Additionally, principal component analysis and OPLS-DA differentiated monoculture and co-culture metabolic profiles, revealed c

SUBMITTER: Abdalla Abdelshafy Mohamad O 

PROVIDER: S-EPMC12361581 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature