Association Between Acute COVID-19 Infection and Long COVID in a Non-Hospitalized Population: A Retrospective Case-Control Study.

ABSTRACT: Long COVID (LC) is a condition characterized by the persistence of physical or psychological symptoms after acute SARS-CoV-2 infection. While its pathophysiology remains unclear, it is essential to identify acute-phase risk factors associated with its development. This study aimed to investigate the association between symptoms during acute COVID-19 and the risk of developing LC, and to evaluate the impact of LC on functional status in a nonhospitalized population. A retrospective observational case-control study was conducted between May 2022 and March 2024 including 434 participants with confirmed SARS-CoV-2 infection. Participants were classified as cases (those with LC; n = 226) or controls (those without LC; n = 208). Data were collected using a structured electronic form, including s

SUBMITTER: Escriva N 

PROVIDER: S-EPMC12361630 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature