Outcomes of Active Treatment for Localised Prostate Cancer After Holmium Laser Enucleation of the Prostate: A Systematic Review and Meta-analysis.

ABSTRACT: Holmium laser enucleation of the prostate (HoLEP) is a common surgical management option for localised prostate cancer (PCa). This review aims to ascertain the safety, and functional and pathological outcomes of active treatments (radical prostatectomy [RP], radiotherapy [RT], and focal therapy) for localised PCa after HoLEP. A systematic review and meta-analysis (PROSPERO registration: CRD42024562687) was conducted, searching the Ovid (Medline) and Embase (Elsevier) databases until October 2024. Comparative and noncomparative studies providing data on patients who underwent HoLEP and subsequent treatment modalities for PCa were included if these reported post- or intraoperative complications, pathological findings, and oncological or functional outcomes. Of the 1567 studies identified, 22

SUBMITTER: Artiles Medina A 

PROVIDER: S-EPMC12361802 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature