Genetic basis and origin of coat color in Leiqiong cattle.

ABSTRACT: Coat color polymorphism in domestic animals provides a robust framework for elucidating mechanisms of species adaptation, domestication, and genomic diversity. Leiqiong cattle, a representative indicine breed from southern China, are predominantly yellow-coated, although a subset exhibits a solid black phenotype. To determine the genetic basis of this variation, a genome-wide association study (GWAS) was performed in 212 Leiqiong bulls. A pronounced association signal was detected on chromosome 6 within the fifth intron of the CORIN gene, providing the first evidence of the potential influence of CORIN on bovine coat color variation. Integration of these results with publicly available genomic datasets and haplotype analyses indicated that the yellow coat phenotype is derived

SUBMITTER: Luo FN 

PROVIDER: S-EPMC12361906 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature