Effect of lateral versus supine positioning on hypoxaemia in sedated adults: multicentre randomised controlled trial.

ABSTRACT:

Objectives

To evaluate the effect of lateral versus supine positioning on incidence of hypoxaemia in sedated patients and to provide evidence based recommendations for respiratory strategies.

Design

Prospective, multicentre, randomised controlled trial.

Setting

14 tertiary hospitals in China, July to November 2024.

Participants

2159 adults (≥18 years) who underwent sedation.

Interventions

Sedated patients were randomly assigned (1:1) to receive either lateral positioning or conventional supine positioning, stratified by study centres.

Main outcome measures

The primary outcome was incidence of hypoxaemia (peripheral oxygen saturation (SpO₂) ≤90%) within the first 10 minutes after positioning. Secondary outcomes included airway rescue int

SUBMITTER: Ye H 

PROVIDER: S-EPMC12362200 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature