Emerging and Legacy Traffic-Related Nitrogen-Containing Organic Compounds (TNOCs) in Pregnant Women: Exposure Levels, Seasonal Variation, and Health Risks.

ABSTRACT: As policymakers increasingly promote emission control technologies and the use of electric vehicles, urban traffic pollution patterns are shifting. Traffic-related nitrogen-containing organic compounds (TNOCs), which represent a critical yet underexplored group of chemicals, have not been comprehensively monitored in humans, particularly among sensitive populations such as pregnant women. In this study, we assessed the internal exposure of pregnant women to 20 emerging and legacy TNOCs by analyzing urine samples after deconjugation (n = 400). The results revealed a frequent detection of TNOCs (median ΣTNOCs: 34.7 ng/mL, adjusted by specific-gravity), with 2-hydroxy-benzothiazole (2-OH-BTH), N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPD-Q), and tolyltriazole (TTR) being t

SUBMITTER: Tao L 

PROVIDER: S-EPMC12362206 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature