Breastfeeding, Prepubertal Adiposity, and Development of Precocious Puberty.

ABSTRACT:

Importance

The incidence of central precocious puberty (CPP) is increasing globally, raising concern about its potential long-term health consequences. However, the association between early-life feeding practices and CPP is poorly understood.

Objective

To investigate the association of breastfeeding during the first 4 to 6 months of life with CPP in boys and girls and whether this association is mediated by prepubertal adiposity.

Design, setting, and participants

This nationwide, retrospective cohort study used health claims data from the South Korean National Health Insurance Service Database between January 1, 2007, and December 31, 2020. Children who underwent routine health checkups at 4 to 6 months (examination 1) and 66 to 71 months (examination 7) were eligibl

SUBMITTER: Choe Y 

PROVIDER: S-EPMC12362225 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature