Ventricular Tachycardia Predicts All-Cause Mortality and Nonsudden Cardiac Death in Nonischemic Cardiomyopathy.

ABSTRACT:

Background

Patients with nonischemic cardiomyopathies (NICMs) are at a risk for end-stage heart failure and death from ventricular arrhythmias. Implanted defibrillators (ICDs) protect against sudden arrhythmic death, but several studies suggest that ventricular arrhythmias are associated with worse outcomes despite ICDs.

Objectives

This study evaluated the relationship of ventricular tachycardia (VT) with total mortality and nonsudden cardiovascular death (NSCVD) in NICM patients with ICDs enrolled in 2 multicentre trials.

Methods

Patient-level data were analyzed from 2 prospective trials: DANISH (Danish Trial to Assess the Efficacy of ICDs in Patients with Nonischemic Systolic Heart Failure on Mortality) (ICD for primary prevention of sudden death) and dilated cardio

SUBMITTER: Omara S 

PROVIDER: S-EPMC12362670 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature