Immobilization of Enzyme-Polymer Hybrids and Nanozymes Through Electrostatic Interactions: Toward Multicatalytic Microreactors with Controlled Nanoarchitecture.

ABSTRACT: The optimal allocation of catalysts and their precise compartmentalization are vital to ensure efficient cascade reactions. The layer-by-layer approach offers the possibility of assembling various building blocks onto templates of different sizes and shapes, thus representing a powerful tool for fabricating multicatalytic reactors with controlled nanoarchitecture. However, this process usually relies on electrostatic interactions between building blocks, which means a limitation when working with natural enzymes. Accordingly, both the loading capacity and control over membrane architecture are compromised by the inherent surface charge of the enzymes. Here, this study introduces a modular strategy to assemble engineered enzyme-polymer hybrids and inorganic nanozymes onto colloidal template

SUBMITTER: Ontoria A 

PROVIDER: S-EPMC12362757 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature