Subcortical and white matter alterations in canine ventriculomegaly: an observational volumetric and voxel-based-morphometry study.

ABSTRACT:

Objective

Ventriculomegaly and hydrocephalus are frequently found during routine clinical imaging, and hydrocephalus in dogs has been shown to alter brain tissue. Although approaches exist to differentiate canine hydrocephalus from ventriculomegaly, information about brain tissue alterations in dogs with ventriculomegaly is lacking. In this observational study, we focused on ventriculomegaly and examined the cerebral anatomical adaptations that accommodate the increased ventricular volume.

Methods

95 neuroradiological normal diagnosed dogs of different breeds were divided into the two groups, ventriculomegaly and control, according to morphological criteria and ventricle-brain-indices as determined by ratio of brain and lateral ventricle wide. Brain volumetry and voxel-based

SUBMITTER: Cyriacks TC 

PROVIDER: S-EPMC12362925 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature