Analysis of HBV infection characteristics and OBI prevalence in pregnant women: a focus on HBcAb + alone or in combination with HBeAb + subgroups in Northwest China.

ABSTRACT:

Background

Hepatitis B virus (HBV) infection is a major global health concern. Serological patterns such as "HBeAb + and HBcAb+" or "HBcAb + only" are typically markers, which may represent either resolved infection or potential occult HBV infection (OBI) with risk of vertical transmission. But OBI in these subgroups of pregnant women in Northwest China remains underreported. This study evaluates OBI prevalence in HBcAb-positive, HBsAb-negative, and HBsAg-negative pregnant women in northwest China and analyzes HBV infection trends from 2015 to 2022.

Methods

This study included 524,319 pregnant women who underwent antenatal screening at Northwest Women and Children's Hospital from January 2015 to December 2022. Epidemiological characteristics of HBV infection were analyzed by

SUBMITTER: Xie Y 

PROVIDER: S-EPMC12362960 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature