Endocrine disrupting chemicals in maternal and umbilical cord plasma and their associations with birthweight in the GUSTO cohort.

ABSTRACT:

Background

With daily exposure to multiple endocrine disrupting chemicals (EDCs), understanding individualized co-exposure patterns could better identify chemicals that threaten health. This is particularly pertinent for the vulnerable fetus during in-utero development, where exposure can have long lasting health consequences. As there is limited information of EDC exposure in Asian maternal-offspring populations, this study aimed to (1) determine levels of a selected range of EDCs (focusing on Substances of Very High Concern by the European Chemical Agency) in maternal and corresponding cord blood plasma, (2) investigate the sociodemographic factors associated with plasma EDC concentrations, and (3) associate EDC-mixtures with birthweight, in a Singapore cohort.

Methods

Tar

SUBMITTER: Ng S 

PROVIDER: S-EPMC12363001 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature