Prognostic value of the combination of serial APACHE II with serum lactate for predicting post-operative mortality in gastrointestinal perforation peritonitis: a prospective cohort study.

ABSTRACT:

Background

Gastrointestinal perforation peritonitis is a life-threatening surgical emergency with high mortality. Early identification of patients at increased risk of poor outcomes is critical for optimizing care. In this study, we aimed to evaluate the prognostic value of combining serial Acute Physiology and Chronic Health Evaluation II (APACHE II) scores and serial serum lactate levels in predicting 30-day postoperative mortality among patients undergoing emergency laparotomy for gastrointestinal perforation peritonitis.

Methods

In this prospective cohort study, 120 adult patients diagnosed with gastrointestinal perforation peritonitis and undergoing emergency laparotomy were enrolled after obtaining ethical approval and informed consent. APACHE II scores and serum lacta

SUBMITTER: Subedi RP 

PROVIDER: S-EPMC12363073 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature