PRMT5 promotes cellulase production by regulating the expression of cellulase gene eg2 through histone methylation in Ganoderma lucidum.

ABSTRACT:

Background

Cellulase can degrade cellulose into reducing sugar, participating in the natural carbon cycle. Simultaneously, cellulase enhances the efficiency and quality of industrial production while also demonstrating significant potential in environmental protection and bioenergy development. Ganoderma lucidum, as a white rot fungus, secret a large amount of cellulase during growth. It is reported that some post-translational modification affects cellulase production. Protein arginine methyltransferase 5 (PRMT5) is involved in transcriptional regulation, RNA processing and signal transduction of biological processes. Therefore, this study primarily investigated whether and how PRMT5 was involved in the regulation of cellulase production in G. lucidum.

Results

Our study fou

SUBMITTER: Li Y 

PROVIDER: S-EPMC12363083 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature