Efficacy of two brands of Mebendazole (500 mg) in the treatment of Ascaris lumbricoides and hookworm infection among school-aged children in South Gondar zone, Northwest Ethiopia: a randomized open label trial.

ABSTRACT:

Background

Parasitic worms remain a serious public health problem in developing countries. Mebendazole is a widely used anthelmintic, but variations in drug efficacy among different brands of mebendazole may impact treatment outcomes. This trial investigated efficacy of two different brands of mebendazole (Vermox^® and X-WORM^®) used in the deworming program and available in local pharmaceutical shops.

Methods

A randomized, open label trial was conducted among 212 children in Alember and Addis Zemen primary schools. Convenient sampling technique was used to select schools and study participants. McMaster egg counting technique was used to determine the intensity of infection. Eligible Ascaris lumbricoides or hookworm infected study participants were rando

SUBMITTER: Malede B 

PROVIDER: S-EPMC12363100 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature