High level of carbapenem resistance and transmission ability of <i>bla</i>_IMP-26 in multidrug-resistant <i>Enterobacter xiangfangensis</i> isolates from China.

ABSTRACT: The emergence of metallo-beta-lactamase gene variants, such as bla_IMP-26, has posed a significant challenge to bacterial infection treatment, drawing considerable attention in public health. This study aims to investigate the resistance mechanism of bla_IMP-26-carrying clinical Enterobacter xiangfangensis in China. bla_IMP-26-harboring carbapenem-resistant Enterobacteriaceae (CRE) isolates were collected from a multicenter study across China. The bla_IMP-26 was identified by polymerase chain reaction (PCR). Multi-locus sequence typing (MLST) and phylogenetic analysis were conducted to investigate the genetic evolutionary characterization of Enterobacteriaceae carrying bla_IMP-26. The

SUBMITTER: Gao Q 

PROVIDER: S-EPMC12363196 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature