Prenatal and Childhood Adverse Events and Child Brain Morphology: A Population-Based Study.

ABSTRACT: Prenatal and childhood adverse events have been shown to be related to children's cognitive and psychological development. However, the influence of early-life adversities on child brain morphology is not well understood and most studies are based on small samples and often examine only one adversity. Thus, the goal of our study is to examine the relationship between cumulative exposures to prenatal and childhood adversities and brain morphology in a large population-based study. Participants included 2,993 children from the Generation R Study, a cohort of children growing up in Rotterdam, the Netherlands. Recruitment was initiated between 2002 and 2006 and the study is currently performing the 17-19 year follow-up wave. Prenatal adversities were reported by mothers at 20-25 weeks of pregn

SUBMITTER: Hidalgo APC 

PROVIDER: S-EPMC12363678 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature