Detection of Cytosolic Ion Concentrations by the Trans-Golgi Network/Early Endosome is Important for Salt Tolerance.

ABSTRACT: Plant survival requires cellular sensing systems that detect and respond to nutrient and ion fluctuations. The ability to monitor and adjust solute concentrations is essential for managing environmental stresses, particularly salt stress, yet the molecular mechanisms underlying cellular ion sensing remain largely unknown. Here, we combine luminal pH measurements with mathematical modelling of ion transport to investigate the role of the Trans-Golgi Network/Early Endosome (TGN/EE) for cellular ion homeostasis. Our results demonstrate that cytosolic concentrations of Cl^-, Na⁺ and K⁺ directly impact ion transport activity at the TGN/EE, thereby influencing luminal pH dynamics. Specifically, we find that the TGN/EE lumen becomes more alkaline when plants are ex

SUBMITTER: McKay D 

PROVIDER: S-EPMC12363952 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature