Organ involvement and laboratory abnormalities associated with tuberculosis disease in systemic lupus erythematosus patients: a systematic review and meta-analysis.

ABSTRACT:

Background

Tuberculosis (TB) is one of the most common infectious diseases in patients with systemic lupus erythematosus (SLE) and often has severe and devastating manifestations. This study aimed to systematically investigate the association between organ involvement and laboratory abnormalities in patients with systemic lupus erythematosus (SLE) associated with tuberculosis disease (TB).

Methods

Relevant studies were obtained from electronic databases, including PubMed, Scopus, Science Direct, and EBSCO from inception to November 2024. The primary outcome was the odds ratio (OR) of TB incidence associated with organ involvement and laboratory abnormalities. Quality of studies was assessed using the Newcastle-Ottawa Scale (NOS). A meta-analysis was performed using R.

Res

SUBMITTER: Tear AA 

PROVIDER: S-EPMC12364090 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature