An insulin-like peptide specific for a cockroach male reproductive gland.

ABSTRACT: The insulin-IGF-signalling (IIS) pathway plays crucial roles in animal physiology. In insects, this pathway uses multiple ligands, insulin-like peptides (ILPs), and a smaller number of insulin receptors (InRs). Consequently, much of the regulation of IIS pathway activity is driven by the expression of ILPs, its timing, tissue specific expression, and mode of action: endocrine, paracrine, or autocrine. In the adult male of the cockroach Blattella germanica, tissue expression and the regulation in relation to food restriction of the ILPs BgILP1-7 is similar to that observed in females. However, we identified the expression of BgILP8, an ILP absent in females, in the conglobate gland of males and only in this organ. BgILP8 expression in the conglobate gland is high during the initial days of

SUBMITTER: Pagone V 

PROVIDER: S-EPMC12364350 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature