Near-random connections support top-down feature-based attentional modulations in early sensory cortex.

ABSTRACT: Top-down feedback from prefrontal cortex (PFC) can enhance the gain of feature selective neurons in early sensory areas that are tuned to behaviorally relevant stimuli (termed feature-based attention). Importantly, feature-based attention can even modulate the gain of neurons that do not respond directly to the spatial location of the relevant stimulus, a phenomenon that is thought to globally prime sensitivity to detect relevant features - irrespective of their location - during visual search. However, the neurons in PFC that are thought to provide top-down feedback typically have high-dimensional tuning for multiple features, so it is unclear how feedback selectively modulates responses in neurons tuned to a relevant stimulus without incidentally causing interference by co-modulating neu

SUBMITTER: Park S 

PROVIDER: S-EPMC12364372 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature