Pretreatment immune-inflammatory prognostic score in predicting clinical outcomes in esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy.

ABSTRACT: In this research, we established, for the first time, an immune-inflammatory prognostic score (IIPS) reflecting the balance of immune and inflammatory status to explore its prognostic value in patients with esophageal squamous cell carcinoma (ESCC) receiving neoadjuvant immunochemotherapy (NICT). In this retrospective study, two hundred and five ESCC patients who received NICT were included. To ascertain whether IIPS was superior to other traditional immune-inflammatory indices (IIIs), we compared their predictive values. The association between IIPS and overall survival (OS)/disease-free survival (DFS) was also investigated. For survival analyses, the Kaplan-Meier method and Cox proportional hazard regression analyses were employed. With a mean age of 64 years (range: 45-75 years), there

SUBMITTER: Zhao Q 

PROVIDER: S-EPMC12364683 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature