Evaluating the Risk of Postoperative Infection and Complications in Lumbar Spine Surgery Patients with Preoperative Methicillin-resistant Staphylococcus aureus (MRSA) Colonization.

ABSTRACT:

Introduction

Preoperative methicillin-resistant Staphylococcus aureus (MRSA) colonization is a known risk factor for surgical site infections (SSIs) in orthopaedic procedures. However, its impact on a comprehensive range of postoperative complications, particularly in elective lumbar spine surgery (LSS), remains unexplored. This study evaluated the association between preoperative MRSA colonization and a comprehensive set of 30-day postoperative outcomes in patients undergoing LSS.

Materials and methods

A retrospective cohort study was conducted using the TriNetX multi-institutional database, including 440,336 patients undergoing elective LSS. Patients were stratified into MRSA-colonized (n = 3,711; 0.84%) and non-colonized controls (n = 436,625). Propensity score matching (

SUBMITTER: Tummala S 

PROVIDER: S-EPMC12364758 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature